sperm-washing

What is semen preparation (sperm washing)?

The process of semen preparation/sperm washing entails separating the healthy sperm that move around from the rest of the semen, leaving only the most efficient sperm to be used in artificial reproduction procedures like IUI and IVF/ICSI.

OVERVIEW

What is semen preparation (sperm washing)?

Once a semen sample is collected, it is processed (or “washed”) in the lab to separate healthy, motile sperm from other components. This prepared sample is then used for fertility treatments such as IUI or IVF/ICSI. There are various techniques used to prepare sperm, such as, Swim up, Density gradient and capillary based methods.

Step by step

How semen preparation works

A laboratory stage within your IUI or IVF cycle. You provide the sample; everything after that happens in the andrology laboratory.

01

Sample collection

Provided at the centre on the day, or thawed from a frozen store.

02

Liquefaction and assessment

The sample is allowed to liquefy, then volume, count and motility are recorded as a baseline.

03

Washing and separation

Density gradient or swim-up techniques separate motile sperm from seminal fluid, dead cells and debris.

04

Concentration and final check

The best motile sperm are concentrated into a small volume and re-assessed before release for use.

05

Insemination or fertilisation

The prepared sample is used for IUI, IVF or ICSI as planned.

FOR WHOM

When semen preparation is used

Semen preparation is recommended for men undergoing fertility treatments where sperm needs to be optimized before use. It’s especially relevant if:

You are having an IUI (Intrauterine Insemination) or IVF/ICSI treatment with your partner.
You suffer from minor male infertility conditions, such as a slight reduction in sperm concentration, motility, or morphology.
You suffer from sexual dysfunction or ejaculation disorders, and you will provide a prepared semen sample.
You wish to store or freeze sperm for future fertility treatments.
You want to maximize the quality and safety of sperm used for conception.

Important to know

Things to keep in mind

When sperm preparation may not be enough

  • No sperm present in the ejaculate - surgical retrieval is needed instead
  • Extremely low motile counts, where ICSI is more appropriate than IUI
  • A sample collected at home and delayed in transit
  • Very high DNA fragmentation, where specialised selection may be added

Preparation improves what is already there.

What to expect

  • Nothing is required of you beyond providing the sample
  • The process takes 45 to 60 minutes while you wait or go about your day
  • The prepared count is always lower than the raw count - this is normal and expected
  • Frozen samples can be used, and are thawed and prepared the same way
  • You are told the prepared parameters before the procedure goes ahead

Alower number after washing is not a bad sign. It is the concentration of what is usable.

Find the right path for your fertility journey

The right treatment depends on your diagnosis. One evaluation consultation is usually enough to know.

  • Honest advice on your treatment options, based on your own tests
  • Transparent pricing before you commit to a cycle
  • 24×7 doctor-supervised medical helpline through your journey
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